Desperate Housewives · A Viewer's Companion
Wisteria Lane looks orderly until you try to remember whose kid is secretly whose. This chart sorts the street by front door, in each housewife's own color: apple red for Bree's Van de Kamps, lawn green for the Scavos, fuchsia for the Solises, sky blue for Susan's house, and ghost lavender for the two mystery households — the Youngs, whose dead wife Mary Alice narrates every episode, and Katherine Mayfair's. Dashed red lines mark the babies who aren't what the lane was told.
Every season of this show runs on one household hiding something from the other four. These are the ones that scramble the family tree.
In the very first scene, perfect neighbor Mary Alice Young shoots herself — then keeps narrating the show from beyond. Why? Years ago she bought a baby, Dana, from a junkie named Deirdre, renamed him Zach, and moved to Wisteria Lane. When Deirdre came back for her son, Mary Alice killed her and buried the toy chest under the pool. A blackmail note — “I know what you did” — did the rest.
The hospital switched Gaby's newborn with the Sanchezes'. So Juanita, raised a Solis, isn't one by blood — and Grace, the daughter Gaby meets in Season 7, is. Gaby barely gets to know her before Grace's parents flee an immigration raid and take her along. Little Celia, for the record, is a genuine Solis.
Katherine Mayfair returns to the lane with a teenage daughter who remembers nothing of her childhood there. Because she didn't live it: the real Dylan died as a child in an accident Katherine covered up, and the girl on the lane is a lookalike orphan Katherine adopted and never told.
When 17-year-old Danielle got pregnant by Edie's nephew, Bree strapped on a prosthetic bump, faked a pregnancy, and raised baby Benjamin as her own son — until Danielle came back for him. On this chart he gets a solid line from Danielle and a dashed red one from his “mother.”
Keep score: Susan divorced Karl, then married Mike twice — divorced in the five-year jump, remarried in the S5 finale. Gaby and Carlos also divorced and remarried each other. Bree buried Rex, divorced Orson, and married Trip Weston in the finale. Only Tom and Lynette wobble to the brink and stay married.
Every episode is narrated by Brenda Strong as the late Mary Alice — the one neighbor who can finally see everything the lane hides. Her suicide opens the series; her ghost's welcome to the newest resident closes it, eight seasons later, with the reveal that the new neighbor has a secret too.
The lane recycles names, swaps babies, and keeps two of everything. One line each.
Same kid. Born Dana to Deirdre; bought and renamed Zach by Paul and Mary Alice. “Dana” is the name on the blackmail trail.
Juanita Solis is Gaby's daughter. Juanita “Mama” Solis was Carlos's mother — the one Andrew hit with his car in Season 1.
Switched at birth. Juanita was raised Solis but isn't one by blood; Grace is Gaby's biological daughter, raised by the Sanchezes.
Twins Preston and Porter, then Parker, Penny, and late-arrival Paige. Stepdaughter Kayla is Tom's with Nora — the sixth kid the show sends away.
The lane's two daughters: Julie is Susan's sensible one (strangled in S6, survives); Danielle is Bree's rebellious one (the teen mom).
All tangled with two women: Mike is Susan's plumber husband; Karl her lawyer ex, who died dating Bree; Orson is Bree's dentist husband — who once ran Mike over.
The real Dylan died as a little girl in Chicago. The Dylan on the lane is the adopted stand-in who doesn't know it.
The two older neighbors: Martha Huber was the blackmailer (Paul strangled her); Karen McCluskey is the babysitter-in-chief who outlives almost everyone.
Not on the family tree, impossible to skip.

Nicollette Sheridan · the fifth housewife
Realtor, man-eater, Susan's rival. Married the serial-killer neighbor Dave, fled the house, and was electrocuted in Season 5.

Kathryn Joosten · the lane's sharp tongue
Cranky neighbor, emergency babysitter, keeper of a freezer with her late husband in it. Takes the lane's last secret to her grave in the finale.

Christine Estabrook · the blackmailer
Sent the note that made Mary Alice pull the trigger. Paul found out and strangled her with a blender cord in Season 1.

Harriet Sansom Harris · Martha's sister
Spent seven seasons destroying Paul Young — including cutting off two of her own fingers to frame him for her “murder.”

Jesse Metcalfe · the gardener
The teenage lawn boy whose affair with Gaby nearly ended the Solis marriage before Season 1 was out. Returns in S6 owning a restaurant.
Scope: the full series — all eight seasons of Desperate Housewives (ABC, 2004–2012), so spoilers run through the series finale. † marks characters dead by the end of the show. Portraits are from the Desperate Housewives Fandom wiki, cropped and self-hosted. The tree keeps to the five core households; spouses like Victor Lang, Trip Weston, Beth Young and Adam Mayfair are left to the text so the street stays readable.